Yes, Virginia, we heard about the increasing job precarity for less skilled and even more qualified workers.
The same happens everywhere, and the gap between rich and poor is growing:
http://www.bbc.com/news/business-32824770
Performance pressure, low salaries, unhealthy work conditions, cheap labour, outsourcing, the disappearance of small and middle-sized, local enterprises, productions, artisanry, business and whole profession branches, swallowed by mass production sites and big profit corporations, and rising unemployment figures have put whole sectors like productions, services, transportation, technologies, science, education, etc., and especially less skilled and also qualified workers under extreme stress, and with that, mental and physical health, and a growing number of working poor and unemployed cannot afford healthcare and are indebted. Also big production sites were restructured, sold or closed down.
https://en.wikipedia.org/wiki/Decline_of_Detroit
http://money.cnn.com/2015/12/01/news/economy/america-poor-in-debt/index.html
https://www.forbes.com/sites/eriksherman/2017/03/14/healthcare-changes-freedom-to-pass-on-unaffordable-insurance/#3364ac1119e3
https://www.theguardian.com/global-development/2011/jan/23/food-speculation-banks-hunger-poverty
http://billmoyers.com/story/whats-killing-american-middle-class/
As to the pharmaceutics and agrochemistry, many widely sold products are hazardous:
https://en.wikipedia.org/wiki/Environmental_impact_of_pharmaceuticals_and_personal_care_products
https://www.mcgill.ca/pfss/files/pfss/agrochemicals_and_their_impact_on_human_health.pdf
https://en.wikipedia.org/wiki/Environmental_impact_of_pesticides
and illegal business, such as criminal drug cartels, sweat shops, prostitution rings, etc., have added to rising insecurity and violence at all levels. As to the problems with alcohol abuse, they persist at all levels of society.
https://www.justice.gov/archive/ndic/pubs38/38661/drugImpact.htm
http://www.covenanteyes.com/2011/09/07/the-connections-between-pornography-and-sex-trafficking/
https://en.wikipedia.org/wiki/Sweatshop
http://www.ias.org.uk/uploads/IAS%20report%20Alcohol%20domestic%20abuse%20and%20sexual%20assault.pdf