There was a cost-cutting motion placed before Congress in the 1899 to close the US Patent Office because "everything worth producing has already been patented". No, I don't think it's all been said.
What amazes me is the number of unique twists authors can give to the same tired old plots so that they come out all shiny new. The same is only partly true of TV presentations and sometimes the twists applied to a show make it ring true. It's only partly successful, of course, which sends the producers, and the purveyors of all manner of consumer goods, in search of fresh entertainment. And they came up with ... reality TV. >:-/
Mrs Didge and I were married in 1960 so we've been together for quite a spell, and we still haven't run out of things to say. I doubt that we ever will.
http://www.onstrategies.com/blog/2007/04/30/close-the-patent-office/